The COVID-19 pandemic demonstrates just how swiftly science can move. Much of the credit belongs to scientists’ ingenuity and grit. Single-cell biology also comes into play. New single-cell datasets and tech tools that support their analysis and the dissemination of results are also helping unlock the mysteries of COVID-19.

The…


On the surface, Cole and Bruce Trapnell’s research couldn’t be more different.

Cole, a computer scientist, builds powerful software tools for studying single cells — the building blocks of life — by the millions. …


Early career researchers are vital to scientific research. They bring new skills and bold leadership that can lead to innovative discoveries.

We believe that collaboration accelerates scientific progress. …


New RFA Supports Technologists to Gain Insights into Health and Disease

The field of single-cell biology is growing rapidly, generating large amounts of data from a variety of tissues and organs — to the tune of 20 million cellular data points alone in cellxgene (​​a CZI-developed tool that allows scientists to visualize datasets from single cells). …


A Conversation with Adele Balmer, a CZI State Science and Technology Policy Fellow, on Connecting Science and Government

Adele Balmer is equally at home bird watching along the Virginia coast, knocking on the doors of politicians in Washington, D.C., and crunching health data at her desktop computer. What connects these activities is her enduring passion for science and for using science to drive positive change.

Balmer is a…


While open source software for science aspires to democratize access and reuse of computational methods by all scientists, it is widely known that open source is predominantly created and maintained by a narrowly defined demographic. …


Python viewer brings together deep learning community and lab scientists

Datasets in science are getting big and unruly. Thankfully, there are people like Carsen Stringer to wrangle them into shape.

A few years ago, she started looking for a way to process terabytes of brain images collected across HHMI’s Janelia Research Campus, where she’s a group leader. Stringer wanted a…


Introducing Aspen, an Open-Source Tool To Help Departments of Public Health Track and Slow the Spread of COVID-19 and Prepare for Future Crises

As COVID-19 quickly spread across California and the U.S. in the spring of 2020, our teams at the Chan Zuckerberg Initiative (CZI) and the Chan Zuckerberg Biohub (CZ Biohub) believed that two approaches had the potential to significantly impact the spread of the virus. The first was increased availability of…


The Carpentries is an organization dedicated to teaching researchers computational skills through a scalable and community-centered model. Since 2019, CZI and the Gordon and Betty Moore Foundation are supporting The Carpentries’ instructor training program and the development of CarpentriesLab — a centralized repository for high-quality, teaching materials contributed by the…


A Conversation with Hannah Valantine and Cori Bargmann

Biomedical science, just like our healthcare system, is rife with structural disparities, inequities, and injustices that are especially experienced by Black, Latinx, and Indigenous people, and other communities of color. …

Chan Zuckerberg Science Initiative

Supporting the science and technology that will make it possible to cure, prevent, or manage all diseases by the end of the century.

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